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Using a high-purity product, like those from Real Peptides, ensures that the observed effects are attributable to the compound being studied and nothing else

Targeting IL-1, IL-22, and chemokine pathways Despite evidence that IL-1 significantly contributes to the progression of ALD in experimental models, clinical trials using IL-1 receptor antagonists [253] (anakinra, NCT01809132) and monoclonal antibodies [254] (canakinumab, NCT03775109) for severe AH have not demonstrated positive outcomes

As a result, IgM OSE have been shown to reduce atherosclerosis in mice and to be inversely associated with coronary artery disease and coronary events in humans 127,128,129,130,131

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6.3 Neural and hormonal pathways involved in gut-brain communication The communication between the gut and brain involves complex neuronal and hormonal networks that might be disturbed following I/R injury