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Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: implications for age-related Macular Degeneration

"About 10% of vitamin B12 deficient patients show reversible melanin skin pigmentation mainly affecting knuckle pads and oral mucosa

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Instead of being flushed away, it starts to attack liver cells, leading to oxidative damage and cellular stress

HECT domain-containing E3 ubiquitin ligase NEDD4L negatively regulates Wnt signaling by targeting dishevelled for proteasomal degradation