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Severe upper gastrointestinal bleeding: If esophagitis remains untreated, it may cause GI bleeding, a condition that can be life threatening

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Too much vasoconstriction can lead to increased risk of: Coronary artery disease High blood pressures Hypertension Headaches Heart attack Stroke Finally, nicotine, and specifically nicotine pouches, can also lead to anxiety, irritability, insomnia and mouth sores from the pouches breaking down mucus membranes in your mouth

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Nutritional Deficiencies and Dehydration The brain needs a steady supply of nutrients to function well