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As a single agent or in combination with cisplatin: On Day 1 of each 21-day cycle, a dose of 500 mg/m2 of Alimta is recommended

Nat Biotechnol 2021, 39:630641

Walega DR et al

Some promising alternatives to sulfur dioxide have been proposed in recent years, including glutathione, both pure and in the form of inactivated yeasts, and Metschnikowia pulcherrima used as a bioprotective agent

Conversely, other ASMs (e.g., lamotrigine, valproate, carbamazepine, gabapentin) are associated with more favorable mood profiles, with some demonstrating inherent mood-stabilizing or even antidepressant properties