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Moreover, Virtual screening and system Pharmacology could be an intriguing approach since they can reveal the connections between unexplored drugs and molecular targets linked to OSA pathogenesis, which would eventually decrease the time required for preclinical testing and increase the chances for success of clinical trials [109, 110]( Fig

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These findings suggest that neutralizing OH might help inhibit genotoxic damage, a protective effect linked to GTCs

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On the other hand, the activation of the neutrophiles takes part directly in the peroxidation of lipids of the membrane and causes directly the destruction of the cell 46