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Figure 4 Although, several classes of lytic inducers have been identified and their mechanism of action has been elucidated in different cell types, only one clinical study has reported a promising outcome in a small fraction of patients with EBV + tumors (337, 338)

[DOI] [PMC free article] [PubMed] [Google Scholar] 131.Crosby L., Davis B., Joshi S., Jardine M., Paul J., Neola M., Barnard N.D

Not surprisingly, the statistical outcomes demonstrated that TLR2 pep-orid-liposome exhibited the best efficacy in reducing tumor burden, as evidenced by the total flux (summed up fluorescence of dorsal and ventral) among the 5 groups (Fig