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European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD) & European Association for the Study of Obesity (EASO)

LIG4 , which encodes LIG4, associates with x-ray cross complementing protein 4 (XRCC4) [127]

Vaario LM, Fritze H, Spetz P, Heinonsalo J, Hanajik P, Pennanen T

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Altogether, our findings suggest that IGF1R depletion in the lung TME of IGF1R-deficient mice delays lung metastasis implantation and progression by reducing the presence of blood vessels, fibroblasts, TAMs and FOXP3 + TILs, as well as by increasing the amount of infiltrating CD4 + and CD8 + T cells (Fig