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Summary Cardiac arrhythmia, or abnormal heart rhythm, can lead to ineffective pumping by the heart and, if prolonged and severe, sudden cardiac death (SCD)

AD is characterized by the accumulation and aggregation of misfolded proteins in brain, the sustained activation of the UPR mediated by the misfold proteins initiates or mediates neurodegeneration (Hoozemans et al., 2005)

If they slow down, you slow down

doi: 10.1056/NEJM198012113032403

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