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10.3390/ijms222111663 98 DaiL.LiuZ.ZhouW.ZhangL.MiaoM.WangL.et al

23,36 However, even this risk remains low, with the highest reported incidence of insulin autoimmune syndrome at 0.017 per 100 000 in Japan

Studies in growth hormone-deficient mice show that while other growth hormone secretagogues increased body fat through growth hormone-independent mechanisms that included increased feeding, ipamorelin's effects on body composition are primarily mediated through its growth hormone-releasing properties