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Patients in whom the frequency of vomiting attacks were reduced by greater or equal to 50% were defined as responders, and the remaining patients were classified as nonresponders

These data argue against HCV-induced autoimmune antibodies leading to Plt destruction because the PAIgG titers increased while Plt counts decreased after eradication of HCV

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The Trial to Reduce Alloimmunization to Platelets Study Group

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