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Although xCT expression is confined to the plasma membrane in normal tissues (36,39), it is upregulated in certain types of cancer, such as colorectal cancer, malignant glioma and non-small cell lung cancer, which increases cystine uptake (4042)

Preeclampsia is classified as newly diagnosed hypertension accompanied by severe organ dysfunction, proteinuria, or uteroplacental dysfunction after 20 weeks of gestation (systolic blood pressure of 140 mmHg or diastolic blood pressure of 90 mmHg for a minimum of two occasions, spaced 4 hours apart)

(Pececnik et al., 2025) These are genuinely interesting mechanistic observations

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thaliana, Hordeum vulgare, Oryza sativa, Physcomitrella patens, Pinus tabulaeformis, Populus trichocarpa , and Solanum lycopersicum ) and selecting only proteins possessing the two regular N- and C-terminal domains (see below), led to the identification of 14 GST classes: phi (F), tau (U), theta (T), zeta (Z), lambda (L), hemerythrin (H), iota (I), ure2p, glutathionyl-hydroquinone reductase (GHR), elongation factor 1B gamma (EF1B), DHAR, tetrachlorohydroquinone dehalogenase (TCHQD), metaxin, and microsomal prostaglandin E synthase type-2 (mPGES-2) (Lallement et al., 2014)