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Statements that describe disease treatment turn a supplement into a drug

Daniels, J

For example, as a coenzyme of SOD2, Mn is involved in redox-sensitive reactions that reduce superoxide (O 2 ) to produce H 2 O 2 , which is then further reduced to produce water by either glutathione peroxidase (GPx) or peroxiredoxins (Prxs) 125,126

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Liver-specific Rictor knockout mice exhibit total hepatic insulin resistance, as evidenced by hyperglycemia and defective lipogenesis

doi: 10.1038/s41419-025-07711-z