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In contrast, one study reported higher GSH levels in the sensorimotor and frontal cortices of older individuals (Hupfeld et al., 2021)

Yu EA, Weaver DR

These changes can cause oxidative modifications to reactive thiols of structurally- or functionally-critical proteins, such as transcription factors 43 , signal transduction molecules 44 or metabolic enzymes 45 , and thereby evoke cellular defense mechanisms against oxidative damage 46

Hell R, Bergmann L: -Glutamylcysteine synthestase in higher plants: catalytic properties and subcellular localization

EGCG has been shown to inhibit the activity of the NF-B transcription factor in various human cancer cells (Peng et al