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H., Pedersen, C

doi: 10.1016/j.tibs.2016.01.001

Shoemaker's research demonstrated that patients with CIRS consistently show severe abnormalities in inflammatory blood markers, including highly elevated TGF-beta1, C4a, and MMP-9, alongside drastically depleted levels of Melanocyte Stimulating Hormone (MSH) and Vasoactive Intestinal Polypeptide (VIP)

Alpha receptor activation produces constriction, mainly in epicardial capacitance vessels when these receptors are mostly found

56:682-685 [PubMed: 23403440] 25

This versatility makes sense, because the reproductive system, nervous system and musculoskeletal system demand such a high amount of energy, and CoQ10 is able to support the high-energy needs of these systems