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Fox Foundation for Parkinsons research

doi: 10.3892/ijmm.2021.4954 33

Collectively, these findings indicate that incretin mimetics provide neuroprotection extending beyond metabolic regulation by targeting multiple pathogenic processes in PD, including mitochondrial dysfunction, neuroinflammation from oxidative stress, sirtuin dysregulation, insulin resistance, and S toxicity (Meissner et al., 2024)

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We included primary in vitro , invertebrate, and PD-specific rodent studies, epidemiologic analyses, and formulation/delivery reports relevant to oxidative stress in PD

Novel luteolin-loaded Chitosan decorated nanoparticles for brain-targeting delivery in a sporadic alzheimers disease mouse model: focus on antioxidant, anti-inflammatory, and amyloidogenic pathways