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[DOI] [PubMed] [Google Scholar] 113.Bordicchia M, Liu D, Amri EZ, Ailhaud G, Dessi-Fulgheri P, Zhang C, et al

Song Z, Zhong X, Li M, Gao P, Ning Z, Sun Z, Song X (2021b) 1-MNA ameliorates high fat diet-induced heart injury by upregulating Nrf2 expression and Inhibiting NF-B in vivo and in vitro

What it does not justify is casual, unsupervised use of a compound whose long-term human safety profile is still being written

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This caution comes mainly from cosmetic formulators rather than from dermatology trials, and the evidence is limited, so it is not something to state as a hard rule