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With just a few exceptions, licensed vaccines for viruses are designed to induce neutralizing antibodies (nAbs) , which can bind to extracellular viruses and inhibit viral entry and infection

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5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT) the enzyme that methylates nicotinamide (NAM) to 1-methylnicotinamide (1-MNA) using S-adenosyl-methionine (SAM) as the methyl donor