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In TNBC, we identified one cluster per patient, with the exception of TNBC-2, which exhibits two clusters (cluster 0 and 5) (Fig

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In PEM, there are insufficient building blocks and energy to make immune cells and immune factors that protect the body from infection and disease

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Acknowledgements The authors thank members of the Powell laboratory for critical review of the manuscript

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After spinning, the filter disks and protein precipitation plate were discarded, and the eluate was immediately used for biomarker analysis in singlecates by Simoa technology on the HD-X platform using a neat protocol (ALZpath Simoa pTau-217 v2 Assay 3 (Quanterix, catalogue number 104371), Simoa Neurology 4-plex E (Quanterix, catalogue number 103607) or Simoa Neurology 2-plex B (Quanterix, catalogue number 103520)

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