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A recent study shows that hUC-MSCs are also useful for the recovery of cognitive ability in a mouse model of AD and that the main actor in the beneficial effect is HGF

Baran N, Lodi A, Dhungana Y, Sweeney, S, Pandey R, Herbrich S, Hof FW, Skwarska A, Kaplan M, Kuruvilla VM, Cavazos A, Ma H, Warmoes M, Veiga DT, Furudate K, Rojas-Sutterin S, Haman A, Harutyunyan K, Daher M, Garcia LM, Piya S, Ruvolo V, Yang W, Shanmugavelandy SS, Feng N, Gay J, Du D, Yang JJ, Tomczak K, Kaminski M, Davis E, Herranz D, Ferando A, Jabbour EJ, DiFrancesco ME, Teachey DT, Horton TM, Rezvani K, Kornblau S, Iurascu MG, Takahashi K, Andreeff M , Marszalek JR, Lorenzi PL, Yu J, Tiziani S, Hoang T, Konpleva M

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The observation that peroxiredoxin expression is responsive to agents that generate oxidative stress provides one potential explanation as to why -cells may express peroxiredoxins and not other antioxidants, like catalase or glutathione peroxidase, as expression of these latter enzymes is not responsive to environmental stressors (40)