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Disclosures: Anand Kulkarni: Nothing to Disclose, Ramyasri Ramagundam: Nothing to Disclose, Zaid Mohammed Gangdany: Nothing to Disclose, Mithun Sharma: Nothing to Disclose, Manasa Alla: Nothing to Disclose, Shantan Venishetty: Nothing to Disclose, Sowmya T R: Nothing to Disclose, Padaki Nagaraja Rao: Nothing to Disclose, Nageshwar Reddy: Nothing to Disclose 1625 LONG-TERM HEPATOPROTECTIVE EFFECTS OF GLP-1RA IN OBESE PATIENTS WITH TYPE 2 DIABETES: A RETROSPECTIVE COHORT STUDY Himsikhar Khataniar 1 Ashni Dharia 1 Aakash Desai 2 Muhammad Ali Butt 1 Michael Babich 1 Nabeeha Mohy-ud-din 1 , 1 Allegheny General Hospital, 2 Mayo Clinic Jacksonville Background: There is an increasing incidence of glucagon-like peptide-1 receptor agonist (GLP-1RA) use for type 2 diabetes mellitus (T2DM) and weight management

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Identification of a novel mechanism for reversal of doxorubicin-induced chemotherapy resistance by TXNIP in triple-negative breast cancer via promoting reactive oxygen-mediated DNA damage