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Adding a reactive substance like vitamin B12 without clinical testing or FDA review introduces additional unknown risks. Lilly said it notified the U.S

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A general feeling of fatigue is often one of the first signs of a B12 deficiency

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In fact, some of the most common symptoms of deficiency include hyperpigmentation of the skin and nails, hair changes, vitiligo, and angular stomatitis, which is a condition that causes cracks and inflammation in the corners of the mouth