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When a strain of Streptomyces coelicolor with a disrupted relA gene was grown under nitrogen limiting conditions both ppGpp and secondary metabolite production were greatly reduced compared to a strain with an intact relA gene [9]

No GH Receptor Binding No IGF-1 Stimulation A defining pharmacological characteristic of HGH Fragment is that it does not bind the growth hormone receptor (GHR) and does not stimulate IGF-1 production