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The term was also used in drug studies to determine who is eligible to participate in a study and to track outcomes, like the degree to which the drug works to address the condition

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In a large recent longitudinal study of healthy aging, in over 1200 healthy people using seven body and three brain modalities, Tian et al showed that body aging phenotypes, particularly of the cardiovascular system, preceded brain measures 244

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Influence of Age on Drug Responses Variation in drug responses may be due to several factors such as: Diminished cardiac output: A reduction in cardiac output reduces hepatic perfusion which may decrease delivery of drug to the liver for metabolism