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In this context, however, the thiol antioxidant glutathione (GSH) represents a dominant defence system with the capacity to neutralize a broad range of both ROS and RNS [39]

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Studies have shown that combining the ratios of CA125 and adiponectin levels can effectively predict patient resistance to platinum drugs, offering potential biomarkers for early resistance identification (148)

[DOI] [PubMed] [Google Scholar] 32.Wang X., Winter D., Ashrafi G., Schlehe J., Wong Y.L., Selkoe D

Philos Trans R Soc B-Biol Sci 355:14651475 Noctor G, Gomez L, Vanacker H, Foyer CH (2002) Interactions between biosynthesis, compartmentation and transport in the control of glutathione homeostasis and signalling