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Acknowledgements This study was supported by National Natural Science Foundation of China (82074355, 82074441) and Shanghai Municipal Health Commission (GWIV-28)

When cells use NAD+, they leave behind some NAM, and the salvage pathway can cycle it back to the beginning of the process

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injection of probes at NIR-I window, and (e) at NIR-II window

In this equilibrium, iron incorporated by cells is stored in ferritin as Fe +3 , which in turn is incorporated into pre-autophagosome structures dependent on anchorage by NCOA4 (nuclear receptor coactivator 4) [40, 41]