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They are not approved for human or veterinary use by the FDA, EMA, or any other regulatory authority

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This is a significant, approx

However, there is still a significant difference between the WL that can be achieved with bariatric surgery and the currently approved obesity pharmacotherapies and there is heterogeneity in treatment responses with GLP-1 RA (for example people with T2D may achieve less WL compared to those without diabetes in clinical trials, despite similar lifestyle interventions) [13, 14]

For researchers investigating skin biology at the cellular and molecular level, this compound is one of the most well-characterised tools available