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There is a perception that individuals who use substances are dangerous or unpredictable, which contributes to fear and discrimination against them

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Materials and Methods Nerve guidance conduits Chitosan/PGLA nerve guidance conduits, which comprise an outer tube of chitosan and luminal fillers of PGLA filaments, were prepared as previously described 28 except that tube-filling filaments were made up of PGLA instead of polyglycolic acid for better biodegradation property

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After raw data pre-processing, peak finding/alignment, and peak annotation using in-house software, metabolites were identified by searching an in-house library containing more than 3,300 standards with library data entries generated from running purified compound standards through the experimental platforms