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We also confirmed that combined inhibition of glutamine and one-carbon metabolism is sufficient to reduce cell proliferation more than treated alone and increase the efficacy of lenvatinib and sorafenib, a multitarget tyrosine kinase inhibitor for patients with ATC

Impairment of mitochondrial calcium buffering links mutations in C9ORF72 and TARDBP in iPS-derived motor neurons from patients with ALS/FTD

In addition, our scRNA-seq analyses revealed a prominent glycolytic signature of IFN + Th1 cells followed by Th2 cells in L