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L-Dopa therapy increases homocysteine concentration in cerebrospinal fluid from patients with Parkinsons disease

Stomach acid and an enzyme called gamma-glutamyl transferase (GGT) break down glutathione before it can reach the small intestine for absorption.[4] The research on this is brutally clear: A 1992 study gave participants a single 3-gram dose of oral glutathione thats ten times what most supplements contain

It is a reasonable step up for normal-to-resilient skin, but the incremental benefit over 1% is not dramatic and depends heavily on the quality of the surrounding formula

doi:10.1016/j.neubiorev.2018.05.005

The logic is that base epithalon has a short half-life and gets degraded quickly, so flooding the system at a higher concentration each day pushes more surviving peptide into target tissues per research dose