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BioRender Template Dopamine's PKA/cAMP pathway intracellular signaling cascade Description This template ilustrates one of dopamine's various intracellular signaling cascades, the PKA/cAMP pathway

That may be a rational design for local GI exposure , where systemic bioavailability may not even be the primary objective

Ramalho R, Soares R, Couto N, Moreira A

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Upon illumination Rg increases from 42.1 (dark) to 52.2 (light), thus revealing an expansion of the protein, while I(0) remains almost unchanged (1.03 10 and 1.08 10 for dark and light state, respectively), indicating that the protein remains in its dimeric form