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Cancer pharmacomicrobiomics: targeting microbiota to optimise cancer therapy outcomes

55-095, Mirkow, Poland

Palmitoylation acts as a checkpoint for MAVS aggregation to promote antiviral innate immune responses

Lysosomal damage is involved in various forms of cell death, such as apoptosis 6,7 , necroptosis 8,9 , pyroptosis 10,11 , and ferroptosis 12,13 , hinting that it is of great significance to the clarification of the potential mechanism of lysosomal damage and further exploration of efficient treatments based on lysosomal quality control (LQC)

Although there is no close relationship between plasma VPA concentrations and the severity of CNS toxicity [11, 86], patients who ingest more than 200 mg/kg VPA and/or have plasma concentrations greater than 180 g/ml usually develop severe CNS depression

[Epub ahead of print] Lee W