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8 Although useful for understanding some features of frataxin, these models could not be studied for one of the main features of the FRDA condition, which is the slow progression

Additionally, the availability of standard substances facilitates accurate quantitative analysis by referencing their spectral information

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The sub-compartmental organization of redoxstasis, based on spatially constrained protein relays (Woo et al., 2010), and the low diffusibility of small redox active compounds such as H 2 O 2 (Bienert and Chaumont, Cysteines and Diseases Secretory Proteins Owing to the importance of structural and regulatory disulfide bonds in membrane and secretory proteins, mutations in luminal cysteines generally have dramatic consequences

Freireich EJ, Kantarjian H, Garcia-Manero G, Ferrajoli A, Koller C, Estrov Z, Kornblau SM , Laddie N, Smith L, Cortes J

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