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The peptide was banned by the World Anti-Doping Agency in 2022 under the S0 category of non-exempt substances

3.2 Steroids As shown in Figure 3, steroids are a class of biologically active compounds in corals, particularly pregnane, cholestane, and ergosterone

Bax oligomerization is associated with the formation of openings in the OMM to allow the release of cytochrome c and other IMS proteins into the cytosol, and hence Bax oligomerization is considered a critical regulatory point in cell death (Youle and Strasser, 2008)

These gross alterations are tangible evidence of the underlying inflammation, necrosis, cholestasis, and potentially related vascular disruptions or initial fibrotic reactions