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Kiyuna LA, Candido DS, Bechara LRG, Jesus ICG, Ramalho LS, Krum B, et al

In addition, the lack of an endogenous equivalent of the HaloTag protein in mammalian cells minimizes the chance of detecting false positives or nonspecific interactions

Furthermore, p53 activates the transcription of antioxidant genes, including SOD2 and catalase, thereby enhancing ROS scavenging and mitigating oxidative stress damage (141)