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doi: 10.1016/J.CARBPOL.2021.118230 68 HedrickT

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Frequency initial loading: To kickstart NAD levels, IV therapy often begins with a loading phase of more frequent sessions, lasking roughly 6 weeks

While no official weight-based protocol exists for retatrutide, the pharmacological principle is straightforward: a larger body distributes the same dose across more tissue, resulting in lower effective tissue concentration