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10.1002/adhm.202100683 Summary Keywords system Xc -/GSH/GPX4 axis, ferroptosis, drug resistance, solid tumor, therapy Citation Li F-J, Long H-Z, Zhou Z-W, Luo H-Y, Xu S-G and Gao L-C (2022) System X c /GSH/GPX4 axis : An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy

Arachidonic acid is released from cellular phospholipids by the enzyme phospholipase A 2 (Fig

Nature 90 457465 Aspinwall R, Rothwell DG, Roldan-Arjona T, Anselmino C, Ward CJ, Cheadle JP, Sampson JR, Lindahl T, et al

Zhu JH, De Mello RA, Yan QL, Wang JW, Chen Y, Ye QH, et al

PubMed Research indicates that retinoids including retinol remain the gold standard for topical anti-aging treatments, though their application is frequently limited by skin irritation and poor tolerability, particularly in sensitive or aged populations