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LGGs with NF1 mutations show greater T cell infiltration, whereas mesenchymal GBMs demonstrate substantial but often ineffective T cell presence

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2h, Supplementary Fig

Loss of NF1 activity leads to hyperactivation of downstream RAS effectors ( NF1 is considered a tumor suppressor gene

The degree of oxidative stress keeps rising and the body's ability to fend it off deteriorates when alcohol consumption is high