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To restore the sodium-potassium gradient across the cell membrane, a sodium-potassium pump requiring ATP pumps sodium out and potassium in

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This layer is responsible for protecting the glutathione from breakdown by digestive enzymes and for its passage through the intestinal wall

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In WD, increased copper concentrations promote the formation of high levels of ROS through Fenton-like reactions (94) or by inhibiting the activity of mitochondrial respiratory chain complexes (95)