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If you are designing a controlled experiment, the cleaner design is usually two separate vials with matched-volume vehicle controls

Gut health responds fastest: Patients with SIBO residual symptoms, chronic GI distress, or post-antibiotic gut damage typically report meaningful improvement in GI symptoms within the first 30 days

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Patients typically take methotrexate once weekly (orally or by subcutaneous injection), alongside folic acid supplementation to minimise side effects

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