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We found significantly lower mean Tajimas D for the top SNPs from the GWAS compared with background SNPs for three of the four traits (Figure 8) due to an excess of low frequency alleles (i.e., low MAFs), consistent with purifying selection (Paape et al., 2013)

Principal component analysis (PCA) was performed using the prcomp function in R stats package (v4.2.1)

Luteolin alleviates inflammation and modulates gut microbiota in ulcerative colitis rats

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One-carbon metabolism generates various products by cycling 1C units from different amino acids and integrating multiple cellular nutritional states (13)

These results are supported by the findings of an in vitro study which exposed human lung adenocarcinoma epithelial cells (A549) to increasing levels of electronic cigarette vapour extract concentrations: 100% vapour extract with one in ten serial dilutions