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The results show that using MK-677 increases markers of bone formation and resorption, such as carboxy-terminal propeptide, procollagen III peptide, and carboxy-terminal cross-linked telopeptide of type I collagen

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It has shown promise in promoting bone growth, as evidenced by studies where its administration counteracted skeletal muscle catabolism induced by glucocorticoids and increased bone mineral content in rats

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The common origin may be the basis for explaining the interaction between the two

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