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Tendon strength comes from parallel fiber alignment and proper cross-linking between collagen molecules

J Pharm Pharmacol 2002

The reduced activity of anorexigenic hormones such as glucagon-like peptide-1 (GLP-1), peptide tyrosine-tyrosine (PYY) and cholecystokinin has been linked to increased food consumption in patients with obesity (21)

Therefore, the relationship between mechanical loading and cell function is considered to be a key component of intervertebral disc function and dysfunction