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The hepatic cytochrome P450 system, crucial for herbal constituent metabolism, demonstrates altered functionality in advanced CKD, potentially compromising the biotransformation of complex phytochemical matrices and increasing susceptibility to hepatotoxic reactions (Chen et al., 2021)

Duloxetine had a better effect on reducing the grade of motor neuropathy and neuropathic pain severity [61]

As the lens accommodates, refraction increases as a result of the increasing power of the lens and, therefore, the amount of chromatic aberration also increases

Apoptosis is mediated by two major pathways: the mitochondrial pathway and the death receptor pathway