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IFN alone was able to downregulate expressions of SLC7A11 and induce ferroptosis

da Silva GH, Alves AV, Duques P, Seva-Pereira T, Soares EC, Escanhoela CA

Between-group comparisons showed that the percentage of patients who experienced worsening of depressive symptoms was significantly different between the CBT-I + CRS group and the nontreated and CRS groups

Though enzymatic ILM degradation has been successful in rodents, there may be a better approach for clinical translation since intravitreal enzymes can elicit an inflammatory response and may cause off-target retinal toxicity