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Moreover, inhibiting the mechanistic target of rapamycin has been demonstrated to decrease the incidence of BIPN in preclinical models (Suzuki et al., 2023)

Aging 14 , 81408149 (2022)

10.1038/s41598-018-33964-0 248 NaumannM.PalA.GoswamiA.LojewskiX.JaptokJ.VehlowA.et al

Curr Opin Gastroenterol 32(6):437442 Barouei J, Moussavi M, Hodgson DM (2012) Effect of maternal probiotic intervention on HPA axis, immunity and gut microbiota in a rat model of irritable bowel syndrome

Retatrutide is currently the most powerful weight loss peptide in clinical development, producing 24.2% average weight loss over 48 weeks in Phase 2 trials