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10,11 Familial chylomicronemia syndrome (FCS) is a rare autosomal recessive disorder caused by genetic variants affecting the lipoprotein lipase (LPL) pathway, characterized by severe hypertriglyceridaemia with triglyceride levels typically of 10 mmol/L (880 mg/dL) or greater and recurrent episodes of acute pancreatitis

Inhibition of these mechanisms by copper efflux results in reduced vascular wall tone, increased myocardial fragility, reduced angiogenesis and ultimately myocardial injury (Fig

Moreover, another vital green tea compound, catechins, proven to alter several biological pathways involved in mitochondria and enhance the anticancer effect of chemotherapy to lessen toxic compounds

[PMC free article: PMC1888033] [PubMed: 2996359] 15

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