cysteine and glutathione deficiency metabolic circuitries: druggable targets in cancer A potent alternative cysteine production

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doi:10.1186/s12916-023-02824-8 Huang T, Redline S

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Specifically, the researchers suggested that the cleavage of caspase-3 and its substrate called Poly ADP-ribose polymerase (PARP) appeared markedly reduced, by ~43% and ~77% respectively, suggesting that the peptide complex may suppress this cascade of programmed cell death

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Virtually all of the robust evidence for BPC-157 comes from animal studies, not human clinical trials