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additionally NAD + can be generated in the mitochondria from NMNAT3 80 , whose activity has been shown to be required in cells 77 , but dispensable in vivo as NAD + can be replenished through other pathways such as import from the cytosol 81

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This extrapolates from effective animal doses converted using standard interspecies scaling factors

See more WADA names substances according to the following convention: For substances that have been given an International Non-proprietary Name (INN), as published by the World Health Organisation, this name is used first