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Group A received oral tranexamic acid 250 mg twice daily in combination with a topical modified Kligman regimen (fluocinolone acetonide 0.01% + hydroquinone 4% + tretinoin 0.05%) and the group B received oral glutathione 500 mg with modified Kligman regimen as above for 8 weeks and then twice in a week at night for the next 4 weeks

Certain medicationsincluding proton pump inhibitors, metformin, and some anticonvulsantsmay affect the absorption or metabolism of specific nutrients

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This results in systemic signaling effects that extend beyond adipose tissue, making these compounds more suitable for studying integrated endocrine regulation rather than isolated metabolic pathways