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Consent for publication The authors give their consents for the publication of contents of this paper to be published in the Cellular and Molecular Life Sciences

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Important in this context is the recent development of drug, a small TAT-TrkB peptide, that prevented TrkB-FL cleavage, improved cognitive performance, ameliorated synaptic plasticity deficits and prevented Tau pathology progression in vivo in a mouse model of AD [233]